Associations between Adjuvant Endocrine Therapy and Onset of Physical and Emotional Concerns among Breast Cancer Survivors
Identifieur interne : 003870 ( Main/Exploration ); précédent : 003869; suivant : 003871Associations between Adjuvant Endocrine Therapy and Onset of Physical and Emotional Concerns among Breast Cancer Survivors
Auteurs : G. J. Van Londen [États-Unis] ; E. B. Beckjord [États-Unis] ; M. A. Dew [États-Unis] ; K. L. Cooper [États-Unis] ; N. E. Davidson [États-Unis] ; D. H. Bovbjerg [États-Unis] ; H. S. Donovan [États-Unis] ; R. C. Thursto [États-Unis] ; J. Q. Morse [États-Unis] ; S. Nutt [États-Unis] ; R. Rechis [États-Unis]Source :
- Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer [ 0941-4355 ] ; 2013.
Abstract
Breast cancer survivors often receive long-term adjuvant endocrine therapy (AET) to reduce recurrence risk. Adherence to AET is suboptimal, which may be due to the experience of symptoms and/or concerns. Few studies have comprehensively assessed self-reported concerns between those who currently, previously or have never received AET. The study objective is to describe self-reported physical and emotional concerns of breast cancer survivors who are current, prior, or never-recipients of AET.
Secondary analysis was performed on a subset of survey data collected in the 2010 LIVE
More than 50% of the participants reported currently experiencing cognitive issues, fatigue, fear of recurrence, emotional distress, and identity/grief issues. Thyroid dysfunction and stigma concerns were more common among participants with prior AET (
Breast cancer survivors who received AET were at risk of developing a variety of physical and emotional concerns, many of which persisted after treatment. These findings suggest the importance of developing individualized, supportive resources for breast cancer survivors.
Url:
DOI: 10.1007/s00520-013-2041-y
PubMed: 24271937
PubMed Central: 3987952
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 003945
- to stream Pmc, to step Curation: 003944
- to stream Pmc, to step Checkpoint: 002495
- to stream Ncbi, to step Merge: 005F83
- to stream Ncbi, to step Curation: 005F83
- to stream Ncbi, to step Checkpoint: 005F83
- to stream Main, to step Merge: 003878
- to stream Main, to step Curation: 003870
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Associations between Adjuvant Endocrine Therapy and Onset of Physical and Emotional Concerns among Breast Cancer Survivors</title><author><name sortKey="Van Londen, G J" sort="Van Londen, G J" uniqKey="Van Londen G" first="G. J." last="Van Londen">G. J. Van Londen</name><affiliation wicri:level="4"><nlm:aff id="A1">University of Pittsburgh, Department of Medicine (Hematology-Oncology, Geriatric Medicine) and Clinical & Translational Science Institute, Pittsburgh, PA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of Pittsburgh, Department of Medicine (Hematology-Oncology, Geriatric Medicine) and Clinical & Translational Science Institute, Pittsburgh, PA</wicri:regionArea><orgName type="university">Université de Pittsburgh</orgName><placeName><settlement type="city">Pittsburgh</settlement><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Beckjord, E B" sort="Beckjord, E B" uniqKey="Beckjord E" first="E. B." last="Beckjord">E. B. Beckjord</name><affiliation wicri:level="4"><nlm:aff id="A2">University of Pittsburgh, Department of Psychiatry, Biobehavioral Medicine in Oncology Program, University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of Pittsburgh, Department of Psychiatry, Biobehavioral Medicine in Oncology Program, University of Pittsburgh Cancer Institute, Pittsburgh, PA</wicri:regionArea><orgName type="university">Université de Pittsburgh</orgName><placeName><settlement type="city">Pittsburgh</settlement><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Dew, M A" sort="Dew, M A" uniqKey="Dew M" first="M. A." last="Dew">M. A. Dew</name><affiliation wicri:level="4"><nlm:aff id="A3">University of Pittsburgh, Departments of Psychiatry, Psychology, Epidemiology and Biostatistics, Pittsburgh, PA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of Pittsburgh, Departments of Psychiatry, Psychology, Epidemiology and Biostatistics, Pittsburgh, PA</wicri:regionArea><orgName type="university">Université de Pittsburgh</orgName><placeName><settlement type="city">Pittsburgh</settlement><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Cooper, K L" sort="Cooper, K L" uniqKey="Cooper K" first="K. L." last="Cooper">K. L. Cooper</name><affiliation wicri:level="1"><nlm:aff id="A4">University of Pittsburgh Cancer Institute Biostatistics Facility, Pittsburgh, PA, United States</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of Pittsburgh Cancer Institute Biostatistics Facility, Pittsburgh, PA</wicri:regionArea><wicri:noRegion>PA</wicri:noRegion></affiliation></author><author><name sortKey="Davidson, N E" sort="Davidson, N E" uniqKey="Davidson N" first="N. E." last="Davidson">N. E. Davidson</name><affiliation wicri:level="1"><nlm:aff id="A5">University of Pittsburgh Cancer Institute and UPMC Cancer Center, Pittsburgh, PA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of Pittsburgh Cancer Institute and UPMC Cancer Center, Pittsburgh, PA</wicri:regionArea><wicri:noRegion>PA</wicri:noRegion></affiliation></author><author><name sortKey="Bovbjerg, D H" sort="Bovbjerg, D H" uniqKey="Bovbjerg D" first="D. H." last="Bovbjerg">D. H. Bovbjerg</name><affiliation wicri:level="4"><nlm:aff id="A6">University of Pittsburgh, Departments of Psychiatry, Psychology, Behavioral & Community Health Science; the Clinical & Translational Science Institute and the Biobehavioral Medicine in Oncology Program, University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of Pittsburgh, Departments of Psychiatry, Psychology, Behavioral & Community Health Science; the Clinical & Translational Science Institute and the Biobehavioral Medicine in Oncology Program, University of Pittsburgh Cancer Institute, Pittsburgh, PA</wicri:regionArea><orgName type="university">Université de Pittsburgh</orgName><placeName><settlement type="city">Pittsburgh</settlement><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Donovan, H S" sort="Donovan, H S" uniqKey="Donovan H" first="H. S." last="Donovan">H. S. Donovan</name><affiliation wicri:level="4"><nlm:aff id="A7">University of Pittsburgh, School of Nursing, Pittsburgh, PA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of Pittsburgh, School of Nursing, Pittsburgh, PA</wicri:regionArea><orgName type="university">Université de Pittsburgh</orgName><placeName><settlement type="city">Pittsburgh</settlement><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Thursto, R C" sort="Thursto, R C" uniqKey="Thursto R" first="R. C." last="Thursto">R. C. Thursto</name><affiliation wicri:level="4"><nlm:aff id="A8">University of Pittsburgh, Departments of Psychiatry and Epidemiology, University of Pittsburgh, PA, USA. USA</nlm:aff><orgName type="university">Université de Pittsburgh</orgName><country>États-Unis</country><placeName><settlement type="city">Pittsburgh</settlement><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Morse, J Q" sort="Morse, J Q" uniqKey="Morse J" first="J. Q." last="Morse">J. Q. Morse</name><affiliation wicri:level="2"><nlm:aff id="A9">Chatham University, Pittsburgh, PA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Pennsylvanie</region></placeName><wicri:cityArea>Chatham University, Pittsburgh</wicri:cityArea></affiliation></author><author><name sortKey="Nutt, S" sort="Nutt, S" uniqKey="Nutt S" first="S." last="Nutt">S. Nutt</name><affiliation wicri:level="1"><nlm:aff id="A10">LIVE<bold>STRONG</bold> Foundation, Austin, TX, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Foundation, Austin, TX</wicri:regionArea><wicri:noRegion>TX</wicri:noRegion></affiliation></author><author><name sortKey="Rechis, R" sort="Rechis, R" uniqKey="Rechis R" first="R." last="Rechis">R. Rechis</name><affiliation wicri:level="1"><nlm:aff id="A10">LIVE<bold>STRONG</bold> Foundation, Austin, TX, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Foundation, Austin, TX</wicri:regionArea><wicri:noRegion>TX</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">24271937</idno><idno type="pmc">3987952</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3987952</idno><idno type="RBID">PMC:3987952</idno><idno type="doi">10.1007/s00520-013-2041-y</idno><date when="2013">2013</date><idno type="wicri:Area/Pmc/Corpus">003945</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">003945</idno><idno type="wicri:Area/Pmc/Curation">003944</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">003944</idno><idno type="wicri:Area/Pmc/Checkpoint">002495</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">002495</idno><idno type="wicri:Area/Ncbi/Merge">005F83</idno><idno type="wicri:Area/Ncbi/Curation">005F83</idno><idno type="wicri:Area/Ncbi/Checkpoint">005F83</idno><idno type="wicri:doubleKey">0941-4355:2013:Van Londen G:associations:between:adjuvant</idno><idno type="wicri:Area/Main/Merge">003878</idno><idno type="wicri:Area/Main/Curation">003870</idno><idno type="wicri:Area/Main/Exploration">003870</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Associations between Adjuvant Endocrine Therapy and Onset of Physical and Emotional Concerns among Breast Cancer Survivors</title><author><name sortKey="Van Londen, G J" sort="Van Londen, G J" uniqKey="Van Londen G" first="G. J." last="Van Londen">G. J. Van Londen</name><affiliation wicri:level="4"><nlm:aff id="A1">University of Pittsburgh, Department of Medicine (Hematology-Oncology, Geriatric Medicine) and Clinical & Translational Science Institute, Pittsburgh, PA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of Pittsburgh, Department of Medicine (Hematology-Oncology, Geriatric Medicine) and Clinical & Translational Science Institute, Pittsburgh, PA</wicri:regionArea><orgName type="university">Université de Pittsburgh</orgName><placeName><settlement type="city">Pittsburgh</settlement><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Beckjord, E B" sort="Beckjord, E B" uniqKey="Beckjord E" first="E. B." last="Beckjord">E. B. Beckjord</name><affiliation wicri:level="4"><nlm:aff id="A2">University of Pittsburgh, Department of Psychiatry, Biobehavioral Medicine in Oncology Program, University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of Pittsburgh, Department of Psychiatry, Biobehavioral Medicine in Oncology Program, University of Pittsburgh Cancer Institute, Pittsburgh, PA</wicri:regionArea><orgName type="university">Université de Pittsburgh</orgName><placeName><settlement type="city">Pittsburgh</settlement><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Dew, M A" sort="Dew, M A" uniqKey="Dew M" first="M. A." last="Dew">M. A. Dew</name><affiliation wicri:level="4"><nlm:aff id="A3">University of Pittsburgh, Departments of Psychiatry, Psychology, Epidemiology and Biostatistics, Pittsburgh, PA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of Pittsburgh, Departments of Psychiatry, Psychology, Epidemiology and Biostatistics, Pittsburgh, PA</wicri:regionArea><orgName type="university">Université de Pittsburgh</orgName><placeName><settlement type="city">Pittsburgh</settlement><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Cooper, K L" sort="Cooper, K L" uniqKey="Cooper K" first="K. L." last="Cooper">K. L. Cooper</name><affiliation wicri:level="1"><nlm:aff id="A4">University of Pittsburgh Cancer Institute Biostatistics Facility, Pittsburgh, PA, United States</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of Pittsburgh Cancer Institute Biostatistics Facility, Pittsburgh, PA</wicri:regionArea><wicri:noRegion>PA</wicri:noRegion></affiliation></author><author><name sortKey="Davidson, N E" sort="Davidson, N E" uniqKey="Davidson N" first="N. E." last="Davidson">N. E. Davidson</name><affiliation wicri:level="1"><nlm:aff id="A5">University of Pittsburgh Cancer Institute and UPMC Cancer Center, Pittsburgh, PA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of Pittsburgh Cancer Institute and UPMC Cancer Center, Pittsburgh, PA</wicri:regionArea><wicri:noRegion>PA</wicri:noRegion></affiliation></author><author><name sortKey="Bovbjerg, D H" sort="Bovbjerg, D H" uniqKey="Bovbjerg D" first="D. H." last="Bovbjerg">D. H. Bovbjerg</name><affiliation wicri:level="4"><nlm:aff id="A6">University of Pittsburgh, Departments of Psychiatry, Psychology, Behavioral & Community Health Science; the Clinical & Translational Science Institute and the Biobehavioral Medicine in Oncology Program, University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of Pittsburgh, Departments of Psychiatry, Psychology, Behavioral & Community Health Science; the Clinical & Translational Science Institute and the Biobehavioral Medicine in Oncology Program, University of Pittsburgh Cancer Institute, Pittsburgh, PA</wicri:regionArea><orgName type="university">Université de Pittsburgh</orgName><placeName><settlement type="city">Pittsburgh</settlement><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Donovan, H S" sort="Donovan, H S" uniqKey="Donovan H" first="H. S." last="Donovan">H. S. Donovan</name><affiliation wicri:level="4"><nlm:aff id="A7">University of Pittsburgh, School of Nursing, Pittsburgh, PA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of Pittsburgh, School of Nursing, Pittsburgh, PA</wicri:regionArea><orgName type="university">Université de Pittsburgh</orgName><placeName><settlement type="city">Pittsburgh</settlement><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Thursto, R C" sort="Thursto, R C" uniqKey="Thursto R" first="R. C." last="Thursto">R. C. Thursto</name><affiliation wicri:level="4"><nlm:aff id="A8">University of Pittsburgh, Departments of Psychiatry and Epidemiology, University of Pittsburgh, PA, USA. USA</nlm:aff><orgName type="university">Université de Pittsburgh</orgName><country>États-Unis</country><placeName><settlement type="city">Pittsburgh</settlement><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Morse, J Q" sort="Morse, J Q" uniqKey="Morse J" first="J. Q." last="Morse">J. Q. Morse</name><affiliation wicri:level="2"><nlm:aff id="A9">Chatham University, Pittsburgh, PA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Pennsylvanie</region></placeName><wicri:cityArea>Chatham University, Pittsburgh</wicri:cityArea></affiliation></author><author><name sortKey="Nutt, S" sort="Nutt, S" uniqKey="Nutt S" first="S." last="Nutt">S. Nutt</name><affiliation wicri:level="1"><nlm:aff id="A10">LIVE<bold>STRONG</bold> Foundation, Austin, TX, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Foundation, Austin, TX</wicri:regionArea><wicri:noRegion>TX</wicri:noRegion></affiliation></author><author><name sortKey="Rechis, R" sort="Rechis, R" uniqKey="Rechis R" first="R." last="Rechis">R. Rechis</name><affiliation wicri:level="1"><nlm:aff id="A10">LIVE<bold>STRONG</bold> Foundation, Austin, TX, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Foundation, Austin, TX</wicri:regionArea><wicri:noRegion>TX</wicri:noRegion></affiliation></author></analytic><series><title level="j">Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer</title><idno type="ISSN">0941-4355</idno><idno type="eISSN">1433-7339</idno><imprint><date when="2013">2013</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec id="S1"><title>BACKGROUND</title><p id="P1">Breast cancer survivors often receive long-term adjuvant endocrine therapy (AET) to reduce recurrence risk. Adherence to AET is suboptimal, which may be due to the experience of symptoms and/or concerns. Few studies have comprehensively assessed self-reported concerns between those who currently, previously or have never received AET. The study objective is to describe self-reported physical and emotional concerns of breast cancer survivors who are current, prior, or never-recipients of AET.</p></sec><sec id="S2"><title>METHODS</title><p id="P2">Secondary analysis was performed on a subset of survey data collected in the 2010 LIVE<bold>STRONG</bold> Survey. Breast cancer survivors (n=1013, mean 5.4 years post-diagnosis) reported on 14 physical and 8 emotional concerns that began after diagnosis and were experienced within 6 months of participation in the survey. Bivariate analyses examined the prevalence of each concern by AET status. The relationships between AET and burden of physical or emotional concerns were modeled with logistic regression.</p></sec><sec id="S3"><title>RESULTS</title><p id="P3">More than 50% of the participants reported currently experiencing cognitive issues, fatigue, fear of recurrence, emotional distress, and identity/grief issues. Thyroid dysfunction and stigma concerns were more common among participants with prior AET (<italic>p</italic><0.01), while fear of recurrence, emotional distress, and concern about appearance were more common among those currently receiving AET (<italic>p</italic><0.01). Fatigue, sexual dysfunction, and pain were more common among prior and current AET recipients (<italic>p</italic><0.01). In adjusted models, receipt of AET was associated with a higher number of physical, but not emotional concerns. A higher number of concerns was associated with younger age, having children, receipt of chemotherapy, longer duration of cancer treatment, and shorter time since diagnosis (<italic>p</italic><0.01).</p></sec><sec id="S4"><title>CONCLUSIONS</title><p id="P4">Breast cancer survivors who received AET were at risk of developing a variety of physical and emotional concerns, many of which persisted after treatment. These findings suggest the importance of developing individualized, supportive resources for breast cancer survivors.</p></sec></div></front></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>Pennsylvanie</li></region><settlement><li>Pittsburgh</li></settlement><orgName><li>Université de Pittsburgh</li></orgName></list><tree><country name="États-Unis"><region name="Pennsylvanie"><name sortKey="Van Londen, G J" sort="Van Londen, G J" uniqKey="Van Londen G" first="G. J." last="Van Londen">G. J. Van Londen</name></region><name sortKey="Beckjord, E B" sort="Beckjord, E B" uniqKey="Beckjord E" first="E. B." last="Beckjord">E. B. Beckjord</name><name sortKey="Bovbjerg, D H" sort="Bovbjerg, D H" uniqKey="Bovbjerg D" first="D. H." last="Bovbjerg">D. H. Bovbjerg</name><name sortKey="Cooper, K L" sort="Cooper, K L" uniqKey="Cooper K" first="K. L." last="Cooper">K. L. Cooper</name><name sortKey="Davidson, N E" sort="Davidson, N E" uniqKey="Davidson N" first="N. E." last="Davidson">N. E. Davidson</name><name sortKey="Dew, M A" sort="Dew, M A" uniqKey="Dew M" first="M. A." last="Dew">M. A. Dew</name><name sortKey="Donovan, H S" sort="Donovan, H S" uniqKey="Donovan H" first="H. S." last="Donovan">H. S. Donovan</name><name sortKey="Morse, J Q" sort="Morse, J Q" uniqKey="Morse J" first="J. Q." last="Morse">J. Q. Morse</name><name sortKey="Nutt, S" sort="Nutt, S" uniqKey="Nutt S" first="S." last="Nutt">S. Nutt</name><name sortKey="Rechis, R" sort="Rechis, R" uniqKey="Rechis R" first="R." last="Rechis">R. Rechis</name><name sortKey="Thursto, R C" sort="Thursto, R C" uniqKey="Thursto R" first="R. C." last="Thursto">R. C. Thursto</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 003870 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 003870 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= LymphedemaV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= PMC:3987952
|texte= Associations between Adjuvant Endocrine Therapy and Onset of Physical and Emotional Concerns among Breast Cancer Survivors
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:24271937" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a LymphedemaV1
| This area was generated with Dilib version V0.6.31. |  |